John Wilkes Booth
Drive up in my Ford, leave a bullet in your head!
(Booth assassinated Abraham Lincoln in Ford's Theatre, and Ford is also the name of a vehicle. Booth had shot Lincoln by shooting him in the head.)
I don't play games but I still leave you dead!
(Connor comes from Assassin's Creed, which is a video game series, where a lot of killing is involved. Booth states that, despite not playing games, he will still leave Connor dead.)
Haytham, Edward, you're the runt of the litter,
(Haytham is Connor's father, and Edward is his gran'dfather, leaving COnnor to be the youngest. Usually, the runt of the litter is the smallest, weakest, and least likely to survive, which Booth is saying that's what Connor is.)
Runnin through the woods, killin poor little critters!
(In the Assassin's Creed games, you can simply pull out your hidden blades, run up, and kill animals.)
You're busy helping Washington, I'm killing Abe Lincoln!
(Connor is known for helping George Washington in Assassin's Creed III. Booth is notorious for assassinating Abraham Lincoln.)
You stab everybody for no apparent reason.
(The player can control Connor to stab enemies on the streets and roof tops between missions for no reason.)
Work for a slave, man, you're worth nothing!
(Connor is the apprentice for Archilles, who is an African American, the most notable race for slaves. Booth says that because of this, he's worth nothing.)
Battle me? Your hood can't hide your bluffing!
(Booth questions Connor's attempt to battle him. The assassins are notable for wearing large hoods. Booth is saying Connor is bluffing, and his hood can't even hide it.)
I drop rhymes like they jumped from a church!
(People who can make lines quickly are said to drop rhymes. Jumping from a church is a notable ability in the Assassin's Creed games, if they land in something to soften the fall....)
Just a little hay, and I still ain't hurt!
(...such as hay. The player loses no health if they land in a hay wagon.)
My hands may be empty, but I still got these!
(Thomas Hickey said, despite assassinating him, Connor's hands were still empty. Despite empty hands, "these" mean hidden blades, which he still has.)
I throw you off a boat like you're Boston Tea!
(The Boston Tea Party occurs in Assassin's Creed III where the player kills the British and throws boxes of tea off the boat. Connor says he throws Booth off of a boat just like the Boston Tea.)